Variophone is often referred as a forerunner of drawn sound system including ANS synthesizer and Oramics.

Variophone (1930) by Evgeny Sholpo-on earliest version, hand drawn waves on film or disc were used to synthesize sound, and later versions were promised to experiment on musical intonations and temporal characteristics of live music performance, however not finished.Oramics (1957) controls sounds by graphics on films Siemens Synthesizer (1959) at Siemens-Studio für elektronische Musik.Included a 4-polyphony synth with 12 oscillators, a sequencer fed with wide paper tape, with output recorded by a disc cutting lathe. RCA Mark II Sound Synthesizer by Herbert Belar and Harry Olson at RCA, a room-filling device built in 1957 for half a million dollars.Punch tape system for earliest studio synthesizers.Music roll for pneumatics system - utilized on player pianos (using piano rolls), Orchestrions, several mechanical organs, etc.Book music (since 1890) for pneumatics system - utilized on several mechanical organs.

Metal disc with punched holes (late 18th century) - utilized on several music boxes such as Polyphon, Regina, Symphonion, Ariston, Graphonola (early version), etc.

Barrel or cylinder with pins (since 9th or 14th century) - utilized on barrel organs, carillons, music boxes.

The following are specifically designed to function primarily as the music sequencers: Many synthesizers, and by definition all music workstations, groove machines and drum machines, contain their own sequencers.

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